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October 2016

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.
01/11/2016
Publication

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs.

Javaheri A, Kruse T, Moonens K, Mejías-Luque R, Debraekeleer A, Asche CI, Tegtmeyer N, Kalali B, Bach NC, Sieber SA, Hill DJ, Königer V, Hauck CR, Moskalenko R, Haas R, Busch DH, Klaile E, Slevogt H, Schmidt A, Backert S, Remaut H, Singer BB, Gerhard M.  Nat Microbiol. Oct 2016. doi: 10.1038/nmicrobiol.2016.189.

COMMENT: Helicobacter pylori is an important human pathogen and causes gastric cancer. Some proteins that bind blood group factors facilitate H. pylori persistence. The authors observed that H. pylori is able to bind gastric epithelium of non-secretors.... + info

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