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January 2016

The Host Shapes the Gut Microbiota via Fecal MicroRNA.
18/09/2016
Publication

The Host Shapes the Gut Microbiota via Fecal MicroRNA.

Liu S, da Cunha AP, Rezende RM, Cialic R, Wei Z, Bry L, Comstock LE, Gandhi R, Weiner HL.  Cell Host Microbe. Jan 2016. doi: 10.1016/j.chom.2015.12.005S1931-3128(15)00497-7.

COMMENT: It is clear that the host shapes the microbiome. The authors describe that miRNAs are among the host factors influencing the microbiome. It has been described for mice and humans that miRNAs are abundant in fecal samples. + info

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children.
18/09/2016
Publication

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children.

Korpela K, Salonen A, Virta LJ, Kekkonen RA, Forslund K, Bork P, de Vos WM.  Nat Commun. 2016. doi: 10.1038/ncomms10410.

COMMENT: It has been described that to take antibiotics in the childhood is associated with increased risk for inflammatory bowel disease, overweight and asthma. + info

Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions.
22/08/2016
Publication

Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions.

Westermann AJ, Förstner KU, Amman F, Barquist L, Chao Y, Schulte LN, Müller L, Reinhardt R, Stadler PF, Vogel J.  Nature. Jan 2016. doi: 10.1038/nature16547.

COMMENT: Dual RNA-seq is used to investigate Salmonella intracellular infection and replication after invasion. In addition of coding RNAs the authors also analyzes lncRNAs and sRNAs. The found expression of 145 known and 189 candidate Salmonella... + info

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer.
22/08/2016
Publication

Species-level resolution of 16S rRNA gene amplicons sequenced through the MinION™ portable nanopore sequencer.

Benítez-Páez A, Portune KJ, Sanz Y.  Gigascience. 2016. doi: 10.1186/s13742-016-0111-z.

COMMENT: 16S rRNA amplicon analysis is a powerful method extensively used to obtain a taxonomic profiling in a metagenomic sample. However, short reads technologies are not able to provide full length 16S sequence. Thus there is a growing... + info

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