image_338

March 2019

Streaming histogram sketching for rapid microbiome analytics.
09/05/2019
Publication

Streaming histogram sketching for rapid microbiome analytics.

Rowe WP, Carrieri AP, Alcon-Giner C, Caim S, Shaw A, Sim K, Kroll JS, Hall LJ, Pyzer-Knapp EO, Winn MD.  Microbiome. 03 2019. doi: 10.1186/s40168-019-0653-2.

COMMENT: Microbiome sequence data is being augmented with large volumes of data, in part as a result of large-scale sequencing initiatives such as the Human Microbiome Project, the Earth Microbiome Project and the Global Ocean Survey. The ability... + info

Hydroxytyrosol Improves Obesity and Insulin Resistance by Modulating Gut Microbiota in High-Fat Diet-Induced Obese Mice.
17/04/2019
Publication

Hydroxytyrosol Improves Obesity and Insulin Resistance by Modulating Gut Microbiota in High-Fat Diet-Induced Obese Mice.

Liu Z, Wang N, Ma Y, Wen D.  Front Microbiol. 2019. doi: 10.3389/fmicb.2019.00390.

COMMENT: Hydroxytyrosol (HT) is the main component of olive oil and it has been shown to have beneficial effects on obesity, inflammation, hyperglycemia, insulin resistance and oxidative stress, among others. However, there is a lack of research... + info

Selection of Multidrug-Resistant Bacteria in Medicated Animal Feeds.
17/04/2019
Publication

Selection of Multidrug-Resistant Bacteria in Medicated Animal Feeds.

Brown EEF, Cooper A, Carrillo C, Blais B.  Front Microbiol. 2019. doi: 10.3389/fmicb.2019.00456.

COMMENT Foodborne outbreaks caused by antimicrobial resistant (AMR) bacteria are an important problem. Animal feeds are supplemented with antibiotics for growth-promotion and prophylaxis. To reduce the risk of fostering the development of antimicrobial... + info

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2.
12/04/2019
Publication

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2.

Caminero A, McCarville JL, Galipeau HJ, Deraison C, Bernier SP, Constante M, Rolland C, Meisel M, Murray JA, Yu XB, Alaedini A, Coombes BK, Bercik P, Southward CM, Ruf W, Jabri B, Chirdo FG, Casqueiro J, Surette MG, Vergnolle N, Verdu EF.  Nat Commun. 03 2019. doi: 10.1038/s41467-019-09037-9.

COMMENT: Celiac disease (CeD) is an autoimmune disorder of the small intestine caused by gluten induced inflammation in some individuals susceptible to genetic and environmental influences.  Some pathogenic bacteria isolated from the duodenum... + info

Unraveling the biophysical underpinnings to the success of multispecies biofilms in porous environments.
09/04/2019
Publication

Unraveling the biophysical underpinnings to the success of multispecies biofilms in porous environments.

Scheidweiler D, Peter H, Pramateftaki P, de Anna P, Battin TJ.  ISME J. Mar 2019. doi: 10.1038/s41396-019-0381-4.

COMMENT: Previous studies on biofilms in porous environments used monospecies systems. To mimic the diversity typically encountered in stream biofilms, Scheidweiler et al, used a natural inoculum containing hundreds of OTUs. This study investigates... + info

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract.
02/04/2019
Publication

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract.

Foley MH, O'Flaherty S, Barrangou R, Theriot CM.  PLoS Pathog. 03 2019. doi: 10.1371/journal.ppat.1007581.

COMMENT: Bile salts hydrolases (BSH) are homotetrameric proteins predominantly expressed in the bacterial cytoplasm. Their function is to initiate bile acids metabolism by the hydrolysis and deconjugation of bile acids. Deconjugated bile acids... + info

Apple consumption is associated with a distinctive microbiota, proteomics and metabolomics profile in the gut of Dawley Sprague rats fed a high-fat diet.
01/04/2019
Publication

Apple consumption is associated with a distinctive microbiota, proteomics and metabolomics profile in the gut of Dawley Sprague rats fed a high-fat diet.

Garcia-Mazcorro JF, Pedreschi R, Yuan J, Kawas JR, Chew B, Dowd SE, Noratto G.  PLoS One. 2019. doi: 10.1371/journal.pone.0212586.

COMMENT: Apple compounds have shown beneficial effects associated with gut microbiota in mice, however, the effect of apple supplementation on health and the gut microbiota is not well understood. In this study the fecal microbiota of rats supplemented... + info

H. pylori eradication with antibiotic treatment causes changes in glucose homeostasis related to modifications in the gut microbiota.
01/04/2019
Publication

H. pylori eradication with antibiotic treatment causes changes in glucose homeostasis related to modifications in the gut microbiota.

Martín-Núñez GM, Cornejo-Pareja I, Coin-Aragüez L, Roca-Rodríguez MDM, Muñoz-Garach A, Clemente-Postigo M, Cardona F, Moreno-Indias I, Tinahones FJ.  PLoS One. 2019. doi: 10.1371/journal.pone.0213548.

COMMENT: Previous studies have associated H. pylori infection and eradication with glucose homeostasis but the mechanisms underlying this association are unclear. This paper analyze whether the infection and eradication treatment of H. pylori may... + info

Variations in early gut microbiome are associated with childhood eczema.
20/03/2019
Publication

Variations in early gut microbiome are associated with childhood eczema.

Zhang Y, Jin S, Wang J, Zhang L, Mu Y, Huang K, Zhao B, Zhang K, Cui Y, Li S.  FEMS Microbiol Lett. Mar 2019.

COMMENT: Gut microbiota plays an important role in human immunological processes, potentially affecting allergic diseases such as eczema. Eczema is the most common chronic inflammatory skin disorder in children and one of the strongest... + info

Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects.
20/03/2019
Publication

Fecal and blood microbiota profiles and presence of nonalcoholic fatty liver disease in obese versus lean subjects.

Yun Y, Kim HN, Lee EJ, Ryu S, Chang Y, Shin H, Kim HL, Kim TH, Yoo K, Kim HY.  PLoS One. 2019. doi: 10.1371/journal.pone.0213692.

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver diseases. In this work, the authors investigate the association between fecal and blood microbiome profiles in people obese versus lean with or without NAFLD, sequencing... + info

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
19/03/2019
Publication

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.

Tomkovich S, Dejea CM, Winglee K, Drewes JL, Chung L, Housseau F, Pope JL, Gauthier J, Sun X, Mühlbauer M, Liu X, Fathi P, Anders RA, Besharati S, Perez-Chanona E, Yang Y, Ding H, Wu X, Wu S, White JR, Gharaibeh RZ, Fodor AA, Wang H, Pardoll DM, Jobin C, Sears CL.  J Clin Invest. Mar 2019. doi: 10.1172/JCI124196124196.

COMMENT: This study reveals that homogenates of biofilm-positive colon mucosa from patients with colorectal cancer and healthy subjects promote tumor development in colorectal cancer mouse models. + info

Relationship between vitamin D status and the vaginal microbiome during pregnancy.
18/03/2019
Publication

Relationship between vitamin D status and the vaginal microbiome during pregnancy.

Jefferson KK, Parikh HI, Garcia EM, Edwards DJ, Serrano MG, Hewison M, Shary JR, Powell AM, Hollis BW, Fettweis JM, Strauss Iii JF, Buck GA, Wagner CL.  J Perinatol. Mar 2019. doi: 10.1038/s41372-019-0343-8.

COMMENT: The authors investigate if plasma 25(OH)D concentrations are associated with the vaginal microbiome. They analyze vaginal 16S rRNA gene taxonomic profiles and plasma 25-hydroxyvitamin D [25(OH)D]... + info

Oral Nickel Changes of Intestinal Microflora in Mice.
14/03/2019
Publication

Oral Nickel Changes of Intestinal Microflora in Mice.

Zhou X, Li J, Sun JL.  Curr Microbiol. Mar 2019. doi: 10.1007/s00284-019-01664-1.

COMMENT: In this work, the authors investigate the effect of oral nickel administration on intestinal microbiome in mice to support some preliminary studies that link the dietary nickel with modifications in the gut microflora.  + info

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy.
05/03/2019
Publication

The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy.

Havel JJ, Chowell D, Chan TA.  Nat Rev Cancer. Mar 2019. doi: 10.1038/s41568-019-0116-x.

Anticancer immunotherapy treatments based on checkpoint inhibitors (ICI) are getting more and more important. For example, antibodies targeting the proteins PD1-PDL1 have been aproved by the FDA as first or second-line treatments for several kinds... + info

The gut microbiota and blood pressure in experimental models.
04/03/2019
Publication

The gut microbiota and blood pressure in experimental models.

Jama HA, Kaye DM, Marques FZ.  Curr Opin Nephrol Hypertens. Mar 2019. doi: 10.1097/MNH.0000000000000476.

COMMENT: This work reviews the evidence that support the relationship between gut microbiota and the development and maintenance of hypertension in experimental models. + info

RSS de esta página