Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn's disease, produces an inflammatory polysaccharide.
Henke MT, Kenny DJ, Cassilly CD, Vlamakis H, Xavier RJ, Clardy J. Proc Natl Acad Sci U S A. Jun 2019.
COMMENT: Studies previously published associated Ruminococcus gnavus with Crohn's disease. In this work the authors discover that the glucorhamnan polysaccharide, which is composed by a rhamnose backbone and glucose side chains, could be a probable... + info
Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer.
Yachida S, Mizutani S, Shiroma H, Shiba S, Nakajima T, Sakamoto T, Watanabe H, Masuda K, Nishimoto Y, Kubo M, Hosoda F, Rokutan H, Matsumoto M, Takamaru H, Yamada M, Matsuda T, Iwasaki M, Yamaji T, Yachida T, Soga T, Kurokawa K, Toyoda A, Ogura Y, Hayashi T, Hatakeyama M, Nakagama H, Saito Y, Fukuda S, Shibata T, Yamada T. Nat Med. Jun 2019. doi: 10.1038/s41591-019-0458-7.
COMMENT: In this article the authors emphasize the multistep nature of the development of colorectal cancer. By means of the integration of shotgun metagenomics and metabolomics data taken from fecal samples the authors identify shifts in the metabolites... + info
Fettweis JM, Serrano MG, Brooks JP, Edwards DJ, Girerd PH, Parikh HI, Huang B, Arodz TJ, Edupuganti L, Glascock AL, Xu J, Jimenez NR, Vivadelli SC, Fong SS, Sheth NU, Jean S, Lee V, Bokhari YA, Lara AM, Mistry SD, Duckworth RA, Bradley SP, Koparde VN, Orenda XV, Milton SH, Rozycki SK, Matveyev AV, Wright ML, Huzurbazar SV, Jackson EM, Smirnova E, Korlach J, Tsai YC, Dickinson MR, Brooks JL, Drake JI, Chaffin DO, Sexton AL, Gravett MG, Rubens CE, Wijesooriya NR, Hendricks-Muñoz KD, Jefferson KK, Strauss JF, Buck GA. Nat Med. Jun 2019. doi: 10.1038/s41591-019-0450-2.
COMMENT: This work has been developed within the integrative Human Microbiome Project (iHMP) to study the relationships between vaginal microbiome and preterm birth searching for microbiome biomarkers useful for evaluating the risk... + info
Boetius A. Nat Rev Microbiol. Jun 2019. doi: 10.1038/s41579-019-0197-2.
COMMENT: A defence of global change microbiology as a research field on its own. Knowing more about microbial life will be key to face the current enviromental challenges. + info
Kamimura BA, De Filippis F, Sant'Ana AS, Ercolini D. Food Microbiol. Jun 2019.
COMMENT: Microbiome characterization of fermented foods can help to improve quality and safety of the products. This is a systematic and wide-range study of the microbiota of Brazilian artisanal cheeses carried out by sequencing of the V3-V4 region... + info
Jagadeesan B, Gerner-Smidt P, Allard MW, Leuillet S, Winkler A, Xiao Y, Chaffron S, Van Der Vossen J, Tang S, Katase M, McClure P, Kimura B, Ching Chai L, Chapman J, Grant K. Food Microbiol. Jun 2019.
COMMENT: The implementation of NGS for food safety and the food industry offers several advantages over the traditional microbiological methods of detection. Whole genome sequencing (WGS) of bacterial food pathogens has been already introduced into... + info