Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, Scheet P, Xu H, Hanash SM, Feng L, Burks JK, Do KA, Peterson CB, Nejman D, Tzeng CD, Kim MP, Sears CL, Ajami N, Petrosino J, Wood LD, Maitra A, Straussman R, Katz M, White JR, Jenq R, Wargo J, McAllister F. Cell. Aug 2019.
COMMENT: This work was developed to investigate the role of the tumor microbiome and the immune system in long-term survival pancreatic adenocarcinoma (PDAC) patients. This interesting study was done using 16S rRNA gene sequencing of... + info
MicroPro: using metagenomic unmapped reads to provide insights into human microbiota and disease associations.
Zhu Z, Ren J, Michail S, Sun F. Genome Biol. 08 2019. doi: 10.1186/s13059-019-1773-5.
COMMENT: This publication describes a data analysis pipeline called MicroPro to analyze metagenomics data especially focused on unknown microorganisms that could be the origin of the unmapped reads. The pipeline analyzes all reads, the mapped... + info
Ducarmon QR, Zwittink RD, Hornung BVH, van Schaik W, Young VB, Kuijper EJ. Microbiol Mol Biol Rev. Aug 2019.
COMMENT: This review summarizes current knowledge on colonization resistance to pathogens mediated by the gut microbiome. + info
Sohn G. Kim et al.. Nature. 21 August 2019.
COMMENT: This work demonstrates how lantibiotics produced by some commensal bacteria are able to inhibit the colonization of the gut by pathogens as important as the vancomycin-resistant Enterococcus faecium (VRE), a leading cause of hospital-acquired... + info
Gu M, Sun J, Qi C, Cai X, Goulette T, Song M, You X, Sela DA, Xiao H. Food Funct. Aug 2019. doi: 10.1039/c9fo01274e.
COMMENT: In this work the authors study the effect of Limonin, widely found in citrus fruits, in the mice microbiome. Mice were fed with a diet containing 0.05% limonin for 9 weeks. Using liquid chromatography-mass spectrum analysis they... + info
Sberro H, Fremin BJ, Zlitni S, Edfors F, Greenfield N, Snyder MP, Pavlopoulos GA, Kyrpides NC, Bhatt AS. Cell. Aug 2019.
COMMENT: This work is oriented to the detection and study of small proteins in human Microbiomes. The authors carried out a comparative genomics analysis on 1,773 human-associated metagenomes from four different body sites: • ... + info
Bi H, Tian Y, Song C, Li J, Liu T, Chen Z, Chen C, Huang Y, Zhang Y. J Med Microbiol. Aug 2019. doi: 10.1099/jmm.0.001058.
COMMENT: In this study 29 bladder cancer patients and 26 non-cancer patients were collected prior to antibiotic administration to analyze their urinary microbiota. The authors detected some differences that suggest that urine microbiome... + info