Pan-genomic analyses identify key Helicobacter pylori pathogenic loci modified by carcinogenic host microenvironments.
Noto JM, Chopra A, Loh JT, Romero-Gallo J, Piazuelo MB, Watson M, Leary S, Beckett AC, Wilson KT, Cover TL, Mallal S, Israel DA, Peek RM. Gut. 10 2018. doi: 10.1136/gutjnl-2017-313863.
COMMENT: Helicobacter pylori is the strongest risk factor for gastric cancer but the pathogenesis appears to depend on bacterial and microenvironmental factors. In this study two carcinogenic microenvironmental factors of the host, iron... + info