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April 2018

Fungal Biodiversity and Their Role in Soil Health.
18/06/2018
Publication

Fungal Biodiversity and Their Role in Soil Health.

Frąc M, Hannula SE, Bełka M, Jędryczka M.  Front Microbiol. 2018. doi: 10.3389/fmicb.2018.00707.

COMMENT: Soil health is directly connected with the production of healthy food which impacts public and animal health. In this mini review Frąc and coworkers focuses on fungal biodiversity and its role in the health of managed soils as well as... + info

Microbiota in obesity: interactions with enteroendocrine, immune and central nervous systems.
23/05/2018
Publication

Microbiota in obesity: interactions with enteroendocrine, immune and central nervous systems.

Mulders RJ, de Git KCG, Schéle E, Dickson SL, Sanz Y, Adan RAH.  Obes Rev. Apr 2018. doi: 10.1111/obr.12661.

COMMENT:  One popular theory for the diet-induced obesity pandemia, for which there is a  considerable evidence base, implicates the composition of intestinal microbiota and its genome (microbiome) which are modifiable by the diet. ... + info

Microbiota-accessible carbohydrates suppress Clostridium difficile infection in a murine model.
29/04/2018
Publication

Microbiota-accessible carbohydrates suppress Clostridium difficile infection in a murine model.

Hryckowian AJ, Van Treuren W, Smits SA, Davis NM, Gardner JO, Bouley DM, Sonnenburg JL.  Nat Microbiol. Apr 2018. doi: 10.1038/s41564-018-0150-6.

COMMENT: In this work the authors show that microbiota-accessible carbohydrates (MACs) in the diet critically influence the Clostridium difficile infection. Using a mouse model of antibiotic-induced Clostridium difficile infeccion they demonstrate... + info

Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults.
29/04/2018
Publication

Drinking alcohol is associated with variation in the human oral microbiome in a large study of American adults.

Fan X, Peters BA, Jacobs EJ, Gapstur SM, Purdue MP, Freedman ND, Alekseyenko AV, Wu J, Yang L, Pei Z, Hayes RB, Ahn J.  Microbiome. Apr 2018. doi: 10.1186/s40168-018-0448-x.

COMMENT: Several previous studies, in both animals and humans, have observed effects of alcohol consumption on oral bacteria. Dysbiosis of the oral microbiome can lead to local oral disease and potentially to cancers of the head, neck, and digestive... + info

Quantitative Assessment of Shotgun Metagenomics and 16S rDNA Amplicon Sequencing in the Study of Human Gut Microbiome.
24/04/2018
Publication

Quantitative Assessment of Shotgun Metagenomics and 16S rDNA Amplicon Sequencing in the Study of Human Gut Microbiome.

Laudadio I, Fulci V, Palone F, Stronati L, Cucchiara S, Carissimi C.  OMICS. Apr 2018. doi: 10.1089/omi.2018.0013.

COMMENT: + info

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing
20/04/2018
Publication

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing

Michael R. Wilson, MD, MAS; Brian D. O’Donovan, MS; Jeffrey M. Gelfand, MD, MA; et al.  JAMA Neurol. April 16, 2018.

COMMENT: The authors present a study of metagenomics NGS (mNGS) where they compare detected organisms in cerebrospinal fluid (CSF) samples of patients of noninfectious neuroimflammatory disorders with organisms detected in CSF samples of chronic... + info

Emerging Technologies for Molecular Diagnosis of Sepsis.
05/04/2018
Publication

Emerging Technologies for Molecular Diagnosis of Sepsis.

Sinha M, Jupe J, Mack H, Coleman TP, Lawrence SM, Fraley SI.  Clin Microbiol Rev. Apr 2018.

COMMENT: Sepsis is a serious and life-threatening clinical condition that generally results from a primary bacterial infection or, less frequently, from a fungal and/or viral infection. Rapid and accurate profiling of infection-causing pathogens remains... + info

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