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December 2018

Genomic sequencing is required for identification of tuberculosis transmission in Hawaii.
14/02/2019
Publication

Genomic sequencing is required for identification of tuberculosis transmission in Hawaii.

Koster KJ, Largen A, Foster JT, Drees KP, Qian L, Desmond E, Wan X, Hou S, Douglas JT.  BMC Infect Dis. Dec 2018. doi: 10.1186/s12879-018-3502-1.

COMMENT: This article highlights the use of next generation whole genome sequencing as a useful tool to resolve Mycobacterium tuberculosis transmission clusters that are indistinguishable by molecular fingerprinting methods. + info

Microbiota and Pathogen Proteases Modulate Type III Secretion Activity in Enterohemorrhagic Escherichia coli.
12/02/2019
Publication

Microbiota and Pathogen Proteases Modulate Type III Secretion Activity in Enterohemorrhagic Escherichia coli.

Cameron EA, Curtis MM, Kumar A, Dunny GM, Sperandio V.  MBio. 12 2018.

COMMENT: This work describes how the commensal Bacteroides thetaiotamicron secretes proteases that cleave the translocon of the Type 3 Secretion System (T3SS) of Enterohemorrhagic Escherichia coli (EHEC) and, thus, enhances effector translocation... + info

Wild bees and their nests host Paenibacillus bacteria with functional potential of avail.
12/02/2019
Publication

Wild bees and their nests host Paenibacillus bacteria with functional potential of avail.

Keller A, Brandel A, Becker MC, Balles R, Abdelmohsen UR, Ankenbrand MJ, Sickel W.  Microbiome. Dec 2018. doi: 10.1186/s40168-018-0614-1.

COMMENT: The genus Paenibacillus includes severe bee pathogens but others are also found in the plant rhizosphere where they have beneficial effects on the plant host. This paper investigates whether the Paenibacillus species found in association... + info

Fiber-associated spirochetes are major agents of hemicellulose degradation in the hindgut of wood-feeding higher termites.
07/02/2019
Publication

Fiber-associated spirochetes are major agents of hemicellulose degradation in the hindgut of wood-feeding higher termites.

Tokuda G, Mikaelyan A, Fukui C, Matsuura Y, Watanabe H, Fujishima M, Brune A.  Proc Natl Acad Sci U S A. 12 2018. doi: 10.1073/pnas.1810550115.

COMMENT: This study investigates the role of the fiber-associated microbial populations in the hindgut of higher termites in wood decomposition and elucidates the principal participants involved in hemicellulose degradation. + info

Evaluating the profound effect of gut microbiome on host appetite in pigs.
29/01/2019
Publication

Evaluating the profound effect of gut microbiome on host appetite in pigs.

Yang H, Yang M, Fang S, Huang X, He M, Ke S, Gao J, Wu J, Zhou Y, Fu H, Chen C, Huang L.  BMC Microbiol. Dec 2018. doi: 10.1186/s12866-018-1364-8.

COMMENT: Gut microbiota has been related with the host appetite control. However, little is known about which microbes are implicated and the way in which those microorganims regulate the host feeding behavior. Based on the results obtained by 16S... + info

Sample storage conditions induce post-collection biases in microbiome profiles.
28/01/2019
Publication

Sample storage conditions induce post-collection biases in microbiome profiles.

Jenkins SV, Vang KB, Gies A, Griffin RJ, Jun SR, Nookaew I, Dings RPM.  BMC Microbiol. Dec 2018. doi: 10.1186/s12866-018-1359-5.

COMMENT: In this work the authors determine the effect of different long term storage strategies on the composition of the murine fecal microbial community by 16S ribosomal RNA (rRNA) gene sequencing.  + info

A chemical defence against phage infection.
24/01/2019
Publication

A chemical defence against phage infection.

Kronheim S, Daniel-Ivad M, Duan Z, Hwang S, Wong AI, Mantel I, Nodwell JR, Maxwell KL.  Nature. 12 2018. doi: 10.1038/s41586-018-0767-x.

COMMENT: In this work the authors report a new chemical anti-phage defence system frequent in Streptomyces that by means of the insertion of three naturally produced molecules into DNA  blocks phage replication. + info

Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.
23/01/2019
Publication

Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.

Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL.  Proc Natl Acad Sci U S A. Dec 2018. doi: 10.1073/pnas.1809700115.

COMMENT: + info

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