Koster KJ, Largen A, Foster JT, Drees KP, Qian L, Desmond E, Wan X, Hou S, Douglas JT. BMC Infect Dis. Dec 2018. doi: 10.1186/s12879-018-3502-1.
COMMENT: This article highlights the use of next generation whole genome sequencing as a useful tool to resolve Mycobacterium tuberculosis transmission clusters that are indistinguishable by molecular fingerprinting methods. + info
Microbiota and Pathogen Proteases Modulate Type III Secretion Activity in Enterohemorrhagic Escherichia coli.
Cameron EA, Curtis MM, Kumar A, Dunny GM, Sperandio V. MBio. 12 2018.
COMMENT: This work describes how the commensal Bacteroides thetaiotamicron secretes proteases that cleave the translocon of the Type 3 Secretion System (T3SS) of Enterohemorrhagic Escherichia coli (EHEC) and, thus, enhances effector translocation... + info
Keller A, Brandel A, Becker MC, Balles R, Abdelmohsen UR, Ankenbrand MJ, Sickel W. Microbiome. Dec 2018. doi: 10.1186/s40168-018-0614-1.
COMMENT: The genus Paenibacillus includes severe bee pathogens but others are also found in the plant rhizosphere where they have beneficial effects on the plant host. This paper investigates whether the Paenibacillus species found in association... + info
Fiber-associated spirochetes are major agents of hemicellulose degradation in the hindgut of wood-feeding higher termites.
Tokuda G, Mikaelyan A, Fukui C, Matsuura Y, Watanabe H, Fujishima M, Brune A. Proc Natl Acad Sci U S A. 12 2018. doi: 10.1073/pnas.1810550115.
COMMENT: This study investigates the role of the fiber-associated microbial populations in the hindgut of higher termites in wood decomposition and elucidates the principal participants involved in hemicellulose degradation. + info
Yang H, Yang M, Fang S, Huang X, He M, Ke S, Gao J, Wu J, Zhou Y, Fu H, Chen C, Huang L. BMC Microbiol. Dec 2018. doi: 10.1186/s12866-018-1364-8.
COMMENT: Gut microbiota has been related with the host appetite control. However, little is known about which microbes are implicated and the way in which those microorganims regulate the host feeding behavior. Based on the results obtained by 16S... + info
Jenkins SV, Vang KB, Gies A, Griffin RJ, Jun SR, Nookaew I, Dings RPM. BMC Microbiol. Dec 2018. doi: 10.1186/s12866-018-1359-5.
COMMENT: In this work the authors determine the effect of different long term storage strategies on the composition of the murine fecal microbial community by 16S ribosomal RNA (rRNA) gene sequencing. + info
Kronheim S, Daniel-Ivad M, Duan Z, Hwang S, Wong AI, Mantel I, Nodwell JR, Maxwell KL. Nature. 12 2018. doi: 10.1038/s41586-018-0767-x.
COMMENT: In this work the authors report a new chemical anti-phage defence system frequent in Streptomyces that by means of the insertion of three naturally produced molecules into DNA blocks phage replication. + info
Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.
Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Proc Natl Acad Sci U S A. Dec 2018. doi: 10.1073/pnas.1809700115.
COMMENT: + info