SUPER-FOCUS: a tool for agile functional analysis of shotgun metagenomic data.
Silva GG, Green KT, Dutilh BE, Edwards RA
Bioinformatics. Feb 2016. doi: 10.1093/bioinformatics/btv584
COMMENT: In this publication a tool for shotgun metagenomics is described: SUPER-FOCUS. It is oriented to functional profiling. The meaning of its name is SUbsystems Profile by databasE Reduction using FOCUS, because it is based in a similarity-based approach to infer function using a reduced reference database of conserved "subsystems". The tool provides the profile of the abundances of these subsystems.
SUPER-FOCUS is implemented in Python, and its source code and the tool website are freely available at https://edwards.sdsu.edu/SUPERFOCUS