Role of priority effects in the early-life assembly of the gut microbiota.
Sprockett D, Fukami T, Relman DA
Nat Rev Gastroenterol Hepatol. 04 2018. doi: 10.1038/nrgastro.2017.173
COMMENT: The authors of this work analyze whether the order and timing of species arrival to gut microbiome determine future microbiome states. They also discuss factors that alter microbial transmission, such as delivery mode, diet and breastfeeding, which can influence the development of a healthy microbiota:
An improved knowledge of priority effects has the potential to inform microorganism-based therapies, such as prebiotics and probiotics, which are aimed at guiding the microbiota towards a healthy state.