Prenatal and postnatal antibiotic exposure influences the gut microbiota of preterm infants in neonatal intensive care units.
Zou ZH, Liu D, Li HD, Zhu DP, He Y, Hou T, Yu JL
Ann Clin Microbiol Antimicrob. Mar 2018. doi: 10.1186/s12941-018-0264-y
COMMENT: To know whether gut microbiota from preterm infants, and drug resistant strains in the neonatal intensive care unit (NICU) were related the authors analyzed 28 preterm infants classified in 2 groups: the PAT (prenatal antibiotic therapy) group (12 cases), and the PAF (prenatal antibiotic free) group (12 cases).
After 16S taxonomic profiling analysis the authors concluded:
... the gut microbiome of preterm infants with prenatal and postnatal antibiotic exposure was similar to resistant bacteria in NICU during the same period.
Antibiotic-resistant bacteria in NICU may play a role in reshaping the early gut microbiota of preterm infants with prenatal and postnatal antibiotic exposure.