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Prenatal and postnatal antibiotic exposure influences the gut microbiota of preterm infants in neonatal intensive care units.

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PubMed ID: 29554907

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Zou ZH, Liu D, Li HD, Zhu DP, He Y, Hou T, Yu JL

Ann Clin Microbiol Antimicrob. Mar 2018. doi: 10.1186/s12941-018-0264-y

COMMENT: To know whether gut microbiota from preterm infants, and drug resistant strains in the neonatal intensive care unit (NICU) were related the authors analyzed 28 preterm infants classified in 2 groups: the PAT (prenatal antibiotic therapy) group (12 cases), and the PAF (prenatal antibiotic free) group (12 cases).

After 16S taxonomic profiling analysis the authors concluded:

... the gut microbiome of preterm infants with prenatal and postnatal antibiotic exposure was similar to resistant bacteria in NICU during the same period. 

Antibiotic-resistant bacteria in NICU may play a role in reshaping the early gut microbiota of preterm infants with prenatal and postnatal antibiotic exposure.

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Raquel Tobes