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Gut Microbiota Profiling: Metabolomics Based Approach to Unravel Compounds Affecting Human Health.

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PubMed ID: 27507964

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Vernocchi P, Del Chierico F, Putignani L

Front Microbiol. 2016. doi: 10.3389/fmicb.2016.01144

COMMENT: The microbiome analysis involves not only metagenomics but also metatranscriptomics, metaproteomics and metabolomics.

In this review the authors highlight the importance of metabolomics as it already known that many metabolites produced by gut bacteria are influencing distant organs and tissues behaviour.

They review:

  • Detection Methods
  • Data analysis
  • Metabolites associated with:
    • Bacterial Metabolism
    • Bacterial Transformed Compounds
  • Different human diseases known to be influenced by The Microbiome

One of the conclusions is the importance of describing / discovering new microbiome associated biomarkers in the future management of many human diseases.

Contributor

Eduardo Pareja