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Evaluating the profound effect of gut microbiome on host appetite in pigs.

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PubMed ID: 30547751

Imagen Publicación

Yang H, Yang M, Fang S, Huang X, He M, Ke S, Gao J, Wu J, Zhou Y, Fu H, Chen C, Huang L

BMC Microbiol. Dec 2018. doi: 10.1186/s12866-018-1364-8

COMMENT: Gut microbiota has been related with the host appetite control. However, little is known about which microbes are implicated and the way in which those microorganims regulate the host feeding behavior. Based on the results obtained by 16S rRNA gene sequencing, the authors identify possible gut bacterial taxa related with feeding behavior and appetite in a porcine model.

OBJECTIVE:

The aim of the present research is to explore the potential impact of gut bacteria on porcine feeding behavior using 16S rRNA gene sequencing, and to identify the possible bacterial taxa influencing porcine appetite.

MAIN RESULTS:

Two enterotypes were identified, which were dominated by Treponema (enterotype 1) and Prevotella (enterotype 2). The Prevotella-predominant enterotype had a significantly higher ADFI value than the Treponema-enterotype. 

Some SCFA-producing bacteria showed negative correlations with feed intake. 

Lactobacillus (OTU62) was detected to negatively associate the ADFI in this study.

CONCLUSIONS:

The present study showed that some bacteria producing SCFAs and lactic acid (e.g. Ruminococcaceae and Lactobacillus) might play an important role in suppressing porcine feed intake, while Prevotella could promote porcine feed intake and might be the keystone bacteria for host appetite control. These results suggested that the gut microbial community might have an important contribution to porcine feeding behavior. The modulation of gut microbiota could be benefit for the control of feed intake in pig industry.

Contributor

Raquel Ruiz-Arroyo