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Commented preprints

 

 

Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities
23/05/2019
Publication

Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities

John Beaulaurier, Elaine Luo, John Eppley, Paul Den Uyl, Xiaoguang Dai, Daniel J Turner, Matthew Pendelton, et al..  doi: https://doi.org/10.1101/619684. Posted in BioRxiv on Apr. 26, 2019..

COMMENT: The main objective was to develop a method to recover viral genome sequences from metagenomics samples making use of long reads. + info

Rapidly processed stool swabs approximate stool microbiota profiles
05/02/2019
Publication

Rapidly processed stool swabs approximate stool microbiota profiles

Nicholas A. Bokulich, Juan Maldonado, Dae-Wook Kang, Rosa Krajmalnik-Brown and J. Gregory Caporaso.

doi: http://dx.doi.org/10.1101/524512. Posted in BioRxiv on Jan. 18, 2019.

COMMENT: Under certain... + info

Mobile genetic element insertions drive antibiotic resistance across pathogens
27/01/2019
Publication

Mobile genetic element insertions drive antibiotic resistance across pathogens

Durrant MG, Li MM,  Siranosian B,  Bhatt AS  doi: http://dx.doi.org/10.1101/527788. Posted in BioRxiv on Jan. 23, 2019.

COMMENT: This work describes a new... + info

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome
24/01/2019
Publication

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

Mark Asquith et al. doi: https://doi.org/10.1101/517813.  Posted in BioRxiv on January 16, 2019.

COMMENT: The main objective of the study is to find out if the discrete gut microbiome features found in patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are a cause or a consequence of having HLA risk alleles. To prove... + info

Oral iron exacerbates colitis and influences the intestinal microbiome
25/08/2018
Publication

Oral iron exacerbates colitis and influences the intestinal microbiome

Authors: Awad Mahalhal, Jonathan M. Williams, Sophie Johnson, Nicholas Ellaby, Carrie A. Duckworth, Michael D. Burkitt, Xuan Liu, Georgina L. Hold, Barry J. Campbell, D. Mark Pritchard, Chris S. Probert

bioRxiv... + info

Architecture of a bacterial type II secretion system
25/08/2018
Publication

Architecture of a bacterial type II secretion system

Authors: Anastasia A Chernyatina and Harry H Low. bioRxiv preprint first posted online Aug. 22, 2018.

COMMENT: In this Preprint the authors, using a fusion of negative stain and cryo-electron... + info

Next-generation sequencing in neuropathological diagnosis of infections of the nervous system
05/09/2016
Publication

Next-generation sequencing in neuropathological diagnosis of infections of the nervous system

Authors: Steven L. Salzberg, Florian P. Breitwieser, Anupama Kumar, Haiping Hao, Peter Burger, Fausto J. Rodriguez, Michael Lim, Alfredo Quiñones-Hinojosa, Gary L. Gallia, Jeffrey A Tornheim, Michael T. Melia, Cynthia L. Sears and Carlos A. Pardo.  Preprint posted in bioRxiv online Feb. 9, 2016.

COMMENT: In this work NGS is used for differential diagnosis of nervous system pathologies whose diagnosis with conventional methods is problematic.  + info

Total RNA Sequencing reveals microbial communities in human blood and disease specific effects
24/08/2016
Publication

Total RNA Sequencing reveals microbial communities in human blood and disease specific effects

Authors: Serghei Mangul, Loes M Olde Loohuis, Anil P Ori, Guillaume Jospin, David Koslicki, Harry Taegyun Yang, Timothy Wu, Marco P Boks, Catherine Lomen-Hoerth, Martina Wiedau-Pazos, Rita M Cantor, Willem M de Vos,René S Kahn, Eleazar Eskin, Roel A Ophoff.  Preprint posted in BioRxiv on  June 7, 2016.

COMMENT: In this preprint the authors demostrate the potential use of total RNA to study microbes that inhabit the blood.  + info

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