Cariogenic Streptococcus mutans produces strain-specific antibiotics that impair commensal colonization
Xiaoyu Tang, Yuta Kudob , Jonathon Baker , Sandra LaBonte , Peter A. Jordan, Shaun M. K. McKinnie, Jian Guo, Tao Huan, Bradley S. Moore and Anna Edlun. bioRxiv Preprint first posted online Sep. 4, 2019; doi: http://dx.doi.org/10.1101/755025..
COMMENT: This work is focused on the analysis of biosynthetic gene clusters in Streptococcus mutans able to produce small active molecules that could give competitive advantage to this abundant bacteria abundant in dental plaque and involved... + info
Resident microbial communities inhibit growth and antibiotic resistance evolution of Escherichia coli in human gut microbiome samples
Michael Baumgartner, Florian Bayer, Angus Buckling, Alex R. Hall. bioRxiv preprint first posted online Aug. 20, 2019; doi: http://dx.doi.org/10.1101/741439 .
COMMENT: This work shows how the resident microbial communities can suppress the growth and colonization by focal Escherichia coli and can prevent the acquisition of antibiotic resistance after beta-lactam antibiotic exposure. + info
Assembly-free single-molecule nanopore sequencing recovers complete virus genomes from natural microbial communities
John Beaulaurier, Elaine Luo, John Eppley, Paul Den Uyl, Xiaoguang Dai, Daniel J Turner, Matthew Pendelton, et al.. doi: https://doi.org/10.1101/619684. Posted in BioRxiv on Apr. 26, 2019..
COMMENT: The main objective was to develop a method to recover viral genome sequences from metagenomics samples making use of long reads. + info
Nicholas A. Bokulich, Juan Maldonado, Dae-Wook Kang, Rosa Krajmalnik-Brown and J. Gregory Caporaso.
doi: http://dx.doi.org/10.1101/524512. Posted in BioRxiv on Jan. 18, 2019.
COMMENT: Under certain... + info
Durrant MG, Li MM, Siranosian B, Bhatt AS doi: http://dx.doi.org/10.1101/527788. Posted in BioRxiv on Jan. 23, 2019.
COMMENT: This work describes a new... + info
HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome
Mark Asquith et al. doi: https://doi.org/10.1101/517813. Posted in BioRxiv on January 16, 2019.
COMMENT: The main objective of the study is to find out if the discrete gut microbiome features found in patients with ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are a cause or a consequence of having HLA risk alleles. To prove... + info
Authors: Awad Mahalhal, Jonathan M. Williams, Sophie Johnson, Nicholas Ellaby, Carrie A. Duckworth, Michael D. Burkitt, Xuan Liu, Georgina L. Hold, Barry J. Campbell, D. Mark Pritchard, Chris S. Probert
bioRxiv... + info
Authors: Anastasia A Chernyatina and Harry H Low. bioRxiv preprint first posted online Aug. 22, 2018.
COMMENT: In this Preprint the authors, using a fusion of negative stain and cryo-electron... + info
Authors: Steven L. Salzberg, Florian P. Breitwieser, Anupama Kumar, Haiping Hao, Peter Burger, Fausto J. Rodriguez, Michael Lim, Alfredo Quiñones-Hinojosa, Gary L. Gallia, Jeffrey A Tornheim, Michael T. Melia, Cynthia L. Sears and Carlos A. Pardo. Preprint posted in bioRxiv online Feb. 9, 2016.
COMMENT: In this work NGS is used for differential diagnosis of nervous system pathologies whose diagnosis with conventional methods is problematic. + info
Authors: Serghei Mangul, Loes M Olde Loohuis, Anil P Ori, Guillaume Jospin, David Koslicki, Harry Taegyun Yang, Timothy Wu, Marco P Boks, Catherine Lomen-Hoerth, Martina Wiedau-Pazos, Rita M Cantor, Willem M de Vos,René S Kahn, Eleazar Eskin, Roel A Ophoff. Preprint posted in BioRxiv on June 7, 2016.
COMMENT: In this preprint the authors demostrate the potential use of total RNA to study microbes that inhabit the blood. + info