Human enteropathogen Clostridium difficile is actively undergoing speciation

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In Nature Genetics it has been reported that a new Clostridium difficile species, selected for metabolizing simple dietary sugars and producing high levels of resistant spores is emerging with a special capacity for healthcare-mediated transmission.

The work reveals that this new species is primed for human transmission in the modern healthcare systems.

The authors conclude:

In summary, our study elucidates how bacterial speciation may prime lineages to emerge and transmit through a process that is accelerated by the modern human diet, the acquisition of antibiotic resistance or healthcare regimes.


Raquel Tobes