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IDO inhibitors to treat metabolic disorders: a new gut microbiota-mediated potential therapy
26/08/2018
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IDO inhibitors to treat metabolic disorders: a new gut microbiota-mediated potential therapy

Studies published in Nature Medicine propose indoleamine 2,3-dioxygenase (IDO) as a potential therapeutic target. IDO influences the tryptophan metabolism exercing a microbiota-dependent control with major consequences on the metabolic disease: Obesity...

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Netbiotix raises €7,5M to bring its lead candidate for inflammatory bowel disease into clinical trials.
06/07/2018
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Netbiotix raises €7,5M to bring its lead candidate for inflammatory bowel disease into clinical trials.

The treatment uses a bacterium found in the gut to prevent and dampen inflammation. Netbiotix, a Paris based Company, develops treatments for inflammatory bowel disease (IBD) that consist of a single microbial strain that interacts with cells in the...

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A link between gut bacteria and liver antitumor immunosurveillance by NKT cells
29/06/2018
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A link between gut bacteria and liver antitumor immunosurveillance by NKT cells

It is known that bile acids are important in liver cancer development and Tim F. Greten and colleagues, authors of this important work, focused their investigations on the role of bile acids in immunosurveillance of liver tumors and...

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Kaleido raises $101M in series C for its microbiome-wide therapy pipeline
28/06/2018
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Kaleido raises $101M in series C for its microbiome-wide therapy pipeline

Kaleido Biosciences, a clinical-stage healthcare company leading the development of novel chemistries to drive functions of the microbiome organ, today announced that it has closed $101 million in an oversubscribed Series C financing. Several new investors...

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Microbiotica (Cambridge, UK) enters $534M deal with Genentech to develop treatments for IBD
12/06/2018
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Microbiotica (Cambridge, UK) enters $534M deal with Genentech to develop treatments for IBD

UK biotech Microbiotica has entered into a multi-year collaboration with Genentech, one of the world’s first biotechs, to develop microbiome-based treatments for inflammatory bowel disease. Microbiotica, based in Cambridge, UK has entered into...

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CDC reports a Multistate outbreak of Shiga toxin-producing Escherichia coli O157:H7 (E. coli O157:H7)
27/04/2018
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CDC reports a Multistate outbreak of Shiga toxin-producing Escherichia coli O157:H7 (E. coli O157:H7)

For the time being 84 cases of people infected with Shiga toxin-producing E. coli O157:H7 from 19 states have been reported to the CDC. 42 of them needed hospitalization and 9 of these developed hemolytic uremic syndrome; no deaths have been reported.  Investigations...

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Seventure Partners, leader in microbiome investment, and Adisseo announce a new venture fund dedicated to innovative Animal Health and Nutrition
12/04/2018
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Seventure Partners, leader in microbiome investment, and Adisseo announce a new venture fund dedicated to innovative Animal Health and Nutrition

Seventure Partners, one of Europe’s leaders in financing innovation and a world-leader in Life science microbiome investment, announces that it has launched AVF, the innovative venture capital fund, targeted at supporting companies in the field...

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Global microbiome sequencing services market to reach USD 1,424.7 Million by 2021
22/02/2018
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Global microbiome sequencing services market to reach USD 1,424.7 Million by 2021

According to a recent report published by Markets&Markets the global microbiome sequencing services market is poised to reach USD 1,424.7 Million by 2021 from USD 538.0 Million in 2016, at a Compound Annual Growth Rate (CAGR) of 21.5% from 2016 to...

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Good bacteria in the gut can produce a chemical signal that affects the human genome
17/01/2018
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Good bacteria in the gut can produce a chemical signal that affects the human genome

Scientists from the Babraham Institute near Cambridge in collaboration with colleagues from Brazil and Italy have discovered a way that good bacteria in the gut can control genes in our cells. The work, published in Nature Communications,...

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Forsyth Institute Researcher Floyd Dewhirst Named as American Association for Advancement of Science Fellow
07/01/2018
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Forsyth Institute Researcher Floyd Dewhirst Named as American Association for Advancement of Science Fellow

Congratulations to Floyd Dewhirst for his election as AAAS Fellow !! The tradition of AAAS Fellows began in 1874. This year, Dewhirst joins 395 members who have been awarded this honor by AAAS because of their distinguished efforts to advance science...

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The Forsyth Institute receives prestigious NIH award to advance research on oral microbiome and all microbe-related fields
07/01/2018
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The Forsyth Institute receives prestigious NIH award to advance research on oral microbiome and all microbe-related fields

the Forsyth Institute has received a $5.4 million award from the National Institutes of Health (NIH) to study oral Microbiome. The prestigious NIH Director's Transformative Research Award has been granted to Forsyth Investigator Christopher Johnston...

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The microbiome influences the patient response to cancer immunotherapy
27/12/2017
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The microbiome influences the patient response to cancer immunotherapy

Recent works demosntate a relationship between the microbiome and the response to immunotherapy in cancer patients. It has been published that highly diverse gut microbiomes are  related with a better response to the immunotherapy. In some...

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Akkermansia muciniphila and Acinetobacter calcoaceticus are increased in Multiple Sclerosis patients gut and induce proinflammatory responses in blood
22/10/2017
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Akkermansia muciniphila and Acinetobacter calcoaceticus are increased in Multiple Sclerosis patients gut and induce proinflammatory responses in blood

Searching for a relationships between gut microbiome and Multiple sclerosis (MS) the authors identified specific bacterial taxa that were significantly associated with MS:  Akkermansia muciniphila and Acinetobacter calcoaceticus, both...

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The finding of Mycobacterium abscessus transmission between patients supposes a new threat for cystic fibrosis treatment
28/02/2017
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The finding of Mycobacterium abscessus transmission between patients supposes a new threat for cystic fibrosis treatment

The most important nontuberculous mycobacterium that infect cystic fibrosis individuals is Mycobacterium abscessus. It produces infections severe for cystic fibrosis patients because is a multidrug-resistant bacteria really difficult...

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Gut microbiome from Parkinson's disease patients induces enhanced motor dysfunction in mice
21/01/2017
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Gut microbiome from Parkinson's disease patients induces enhanced motor dysfunction in mice

Finally a clear relationship between the gut microbiome and Parkinson's disease (PD) has been pubished in Cell. In the article entitled "Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease"...

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The #2 USA Hospital Cleveland Clinic Unveils 2017 Top 10 Medical Innovations: #1 The Microbiome
01/11/2016
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The #2 USA Hospital Cleveland Clinic Unveils 2017 Top 10 Medical Innovations: #1 The Microbiome

A panel of top doctors and researchers presents the advancements with the power to transform healthcare in 2017. The top 10 innovations were unveiled to more than 1,600 doctors, entrepreneurs and other industry leaders at the 14th annual Cleveland...

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A coat for bacteria: layer-by-layer encapsulation for beneficial bacteria delivery
18/09/2016
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A coat for bacteria: layer-by-layer encapsulation for beneficial bacteria delivery

A good idea of a team of MIT: scientists of the Jaklenec group have developed a new way for delivering beneficial bacterial to the human gut. They coat bacteria with polymer layers similar to those of some pharmaceutical preparations. This coat protects...

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2016 MOBIO MICROBIOME AWARD WINNERS
18/09/2016
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2016 MOBIO MICROBIOME AWARD WINNERS

This year the winners of the MOBIO MICROBIOME AWARD were announced on September 15, 2016. The first prize was for Catherine Burke for her work in the characterization of the microbiome of human depression. The second prize...

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Synlogic Proprietary Synthetic Biotic Receives FDA Orphan Drug Designation for treatment of urea cycle disorders
18/09/2016
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Synlogic Proprietary Synthetic Biotic Receives FDA Orphan Drug Designation for treatment of urea cycle disorders

Synlogic has got the U.S. Food and Drug Administration (FDA) orphan drug designation to it's program involving a live Escherichia coli Nissle bacterium modified to assimilate ammonia for treatment of urea cycle disorders. Synlogic...

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Vedanta Biosciences Granted Second U.S. Patent Covering Methods of Treating Autoimmune Disease
18/09/2016
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Vedanta Biosciences Granted Second U.S. Patent Covering Methods of Treating Autoimmune Disease

The United States Patent and Trademark Office (USPTO) has issued U.S. Patent No. 9,421,230. The patent broadly covers methods of treating autoimmune disease with mixtures of Clostridium live bacterial strains. The patented technology is based on ground-breaking...

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Mouse microbes may make scientific studies harder to replicate
21/08/2016
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Mouse microbes may make scientific studies harder to replicate

Science Magazine history pointing to a very interesting lab history raising important concers about reproductibility of experimental results when they involve mice. When lab mice are used it is supossed that they are identical whe you are using same strain...

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DC-Area Hospital Evacuates NICU After Dangerous Bacteria Found
10/08/2016
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DC-Area Hospital Evacuates NICU After Dangerous Bacteria Found

A hospital in the Washington, D.C., area has started to move patients from its neonatal intensive care unit (NICU) after Pseudomonas bacteria were found on three patients, hospital officials said. The bacteria had been found in a water...

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T Lymphocyte: Colorized scanning electron micrograph of a T lymphocyte.

Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health

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